HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 89454181, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Water | HCID 962 | — |
| Reactant | HCID 89454041 | HCID 89454041 | — |
| Reactant | HCID 131733668 | HCID 131733668 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 89454181 | HCID 89454181 | 94% |
Reaction Steps
The product is obtained according to the procedure described in Step 1.7. by treating 8-bromo-7-(pyrid-2-yl-1-(tetrahydro-2H-pyran-2-yl)-5-(2,2,2-trifluoroethyl)-1,5-dihydro-4H-pyrazolo[4,3-c]quinolin-4-one and 8-bromo-7-(pyrid-2-yl)-2-(tetrahydro-2H-pyran-2-yl)-5-(2,2,2-trifluoroethyl)-1,5-dihydro-4H-pyrazolo[4,3-c]quinolin-4-one with 4M HCl in dioxane, in the form of a white powder (hydrochloride, 0.4 H2O; yield 94%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09169246B2 |
| Source dataset | uspto-grants-2015_10 |
| ORD ID | ord-4aed1ec2ed3f4e45ba937318719d0bb9 |
| Source note | uspto-grants-2015_10 |