2-ethyl-5-nitro-2H-pyrazole-3-carboxylic acid methyl ester → 5-amino-2-ethyl-2H-pyrazole-3-carboxylic acid methyl ester

Participants

Reaction Steps

To 2-ethyl-5-nitro-2H-pyrazole-3-carboxylic acid methyl ester (526, 1.30 g, 6.53 mmol) in methanol (60.0 mL) was added 20% Pd(OH)2C (0.1 g). The reaction was stirred under an atmosphere of hydrogen overnight. The reaction was filtered and concentrated to give a light yellow solid (527, 1.0 g, 90.6%).

Provenance & Evidence