2,4-Dichloropyrimidine → 3-(2-Chloropyrimidin-4-yl)-5-morpholinobenzonitrile

HRID 175481Notes

Reaction equation

HRID 175481 reaction equation
[Br:32][c:33]1[cH:34][c:35]([C:45]#[N:46])[cH:36][c:37]([N:38]2[CH2:39][CH2:40][O:41][CH2:42][CH2:43]2)[cH:44]1.[Cl:1][c:2]1[n:3][cH:4][cH:5][c:6]([Cl:8])[n:7]1.[O:9]1[CH2:10][CH2:11][N:12]([c:15]2[cH:16][c:17]([C:18]#[N:19])[cH:20][c:21]([B:23]3[O:24][C:25]([CH3:26])([CH3:27])[C:28]([CH3:29])([CH3:30])[O:31]3)[cH:22]2)[CH2:13][CH2:14]1>>[Cl:1][c:2]1[n:3][cH:4][cH:5][c:6](-[c:21]2[cH:20][c:17]([C:18]#[N:19])[cH:16][c:15]([N:12]3[CH2:11][CH2:10][O:9][CH2:14][CH2:13]3)[cH:22]2)[n:7]1

Participants

4

Reactant 3

HCID 775312,4-DichloropyrimidineHCID 446273673-Bromo-5-morpholinobenzonitrileHCID 446274743-Morpholino-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile

Product 1

HCID 446274803-(2-Chloropyrimidin-4-yl)-5-morpholinobenzonitrile

Sources & evidence

ORD record
ord-68d950b02796417883c476ccf4594ef4
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

Loading…