Ethyl Acetate → (+)-3,3-Difluoro-1-hydroxycyclopentanecarboxylic acid

HRID 175482Notes

Reaction equation

HRID 175482 reaction equation
[CH3:19][CH2:20][O:21][C:22]([CH3:23])=[O:24].[F:1][C:2]1([F:18])[CH2:3][C:4]([C:7](=[O:8])[O:9][CH2:10][c:11]2[cH:12][cH:13][cH:14][cH:15][cH:16]2)([OH:17])[CH2:5][CH2:6]1>>[F:1][C:2]1([F:18])[CH2:3][C:4]([C:7](=[O:8])[OH:9])([OH:17])[CH2:5][CH2:6]1

Participants

3

Reactant 2

HCID 8857Ethyl AcetateHCID 68718275(+)-Benzyl 3,3-difluoro-1-hydroxycyclopentanecarboxylate

Product 1

HCID 68715806(+)-3,3-Difluoro-1-hydroxycyclopentanecarboxylic acid

Sources & evidence

ORD record
ord-7543e8c3e7164cacb1cc4da506ad1643
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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