HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Nitrate → 2-Amino-5-bromo-4-fluoro-6-methyl-3-nitrobenzonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Nitrate | HCID 24434 | — |
| Reactant | 6-Amino-3-bromo-4-fluoro-2-methylbenzonitrile | HCID 54107179 | — |
| Solvent | Sulfuric Acid | HCID 1118 | — |
| Product | 2-Amino-5-bromo-4-fluoro-6-methyl-3-nitrobenzonitrile | HCID 86097375 | — |
Reaction Steps
With cooling with ice, potassium nitrate (2.43 g, 21.8 mmol) was gradually added to a concentrated sulfuric acid (20 ml) solution of 6-amino-3-bromo-4-fluoro-2-methylbenzonitrile (I-265) (5.00 g, 21.8 mmol). After stirring for 10 minutes, the reaction liquid was poured into ice and stirred.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07737166B2 |
| Source dataset | uspto-grants-2010_06 |
| ORD ID | ord-95eefb43a22349c2885c61ec4eb100ed |
| Source note | uspto-grants-2010_06 |