Trifluoroacetic acid → Trifluoroacetic acid

Participants

Reaction Steps

To a solution of material from Example 10 (27 mg, 0.07 mmol) in CH2Cl2 (6 mL) is added trifluoroacetic acid (2.5 mL, 32.4 mmol). The resulting solution is stirred at room temperature for 1 h, then evaporated to dryness over 18 h to give the title compound as a TFA salt that is used crude, and in its entirety in the next step. LC/MS (Condition A): ret. T=2.45 min, (M+1-H)+ 334.08.

Provenance & Evidence