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HRID1755573

反应详情

EQUATION

反应方程式

HRID 1755573 的结构方程式

REACTANTS

反应物

3
结构：NCCOCCO
HCID13578

2-(2-Aminoethoxy)ethanol

C4H11NO2

结构：Cc1c(C)c2c(c(C)c1O)CCC(C)(C(=O)O)O2
HCID40634

Trolox

C14H18O4

结构：O=C(n1ccnc1)n1ccnc1
HCID68263

1,1'-Carbonylbis(1H-imidazole)

C7H6N4O

PRODUCTS

生成物

1
结构：Cc1c(C)c2c(c(C)c1O)CCC(C)(C(=O)NCCOCCO)O2
HCID67263063

未命名化合物

收率 82.5%

PROCEDURE

实验过程

Following the amide coupling procedure described in protocol A, 501 mg 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid (2.0 mmol), 360 mg CDI (2.23 mmol) and 231 mg 2-(2-aminoethoxy)ethanol (2.19 mmol) produced 557 mg of 6-hydroxy-N-(2-(2-hydroxyethoxy)ethyl)-2,5,7,8-tetramethylchroman-2-carboxamide as an amorphous white solid.