Water → 1-Ethynyl-4-propylbenzene

Participants

Reaction Conditions

Reaction Steps

33 g of 3-methyl-1-(4'-propylphenyl)-1-butyn-3-ol was dissolved in 320 ml of toluene in nitrogen atmosphere, and 2 g of sodium hydride (60% in paraffin liquid) was added thereto. This was stirred for 6 hours at 60° C. The reaction solution was poured into 300 ml of water, extracted with chloroform and washed three times with water. Toluene and chloroform were removed by distillation, and the residue was distilled under reduced pressure (b.p. 60° to 63° C./4 mmHg) to obtain 16 g of 4-propylphenylacetylene.

Provenance & Evidence