反应详情

温度

60 °C

33 g of 3-methyl-1-(4'-propylphenyl)-1-butyn-3-ol was dissolved in 320 ml of toluene in nitrogen atmosphere, and 2 g of sodium hydride (60% in paraffin liquid) was added thereto. This was stirred for 6 hours at 60° C. The reaction solution was poured into 300 ml of water, extracted with chloroform and washed three times with water. Toluene and chloroform were removed by distillation, and the residue was distilled under reduced pressure (b.p. 60° to 63° C./4 mmHg) to obtain 16 g of 4-propylphenylacetylene.

1. additionwas added
2. extractionextracted with chloroform
3. washwashed three times with water
4. customToluene and chloroform were removed by distillation
5. distillationthe residue was distilled under reduced pressure (b.p. 60° to 63° C./4 mmHg)