Dimethylamine → HCID 86748822, compound

HRID 1755679Notes

Reaction equation

HRID 1755679 reaction equation
[Cl:1][C:2]1[N:7]=[CH:6][C:5]([CH2:8][N:9]([C:11]([NH:16][CH3:17])=[CH:12][N+:13]([O-:15])=[O:14])[CH3:10])=[CH:4][CH:3]=1.[CH2:18]=O.[CH3:20][NH:21][CH3:22]>C(#N)C>[Cl:1][C:2]1[N:7]=[CH:6][C:5]([CH2:8][N:9]([C:11]([NH:16][CH3:17])=[C:12]([N+:13]([O-:15])=[O:14])[CH2:20][N:21]([CH3:18])[CH3:22])[CH3:10])=[CH:4][CH:3]=1

Participants

5

Reactant 3

HCID 674DimethylamineHCID 712FormaldehydeHCID 85054604N-[(6-Chloro-3-pyridinyl)methyl]-N,N′-dimethyl-2-nitro-1,1-ethenediamine

Product 1

HCID 86748822HCID 86748822, compoundYield 102.8%

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Procedure

A mixture of 1-[N-(6-chloro-3-pyridylmethyl)-N-methylamino]-1-methylamino-2-nitroethylene(0.39 g), 37% aqueous solution of formaldehyde (0.16 g), 50% aqueous solution of dimethylamine (0.18 g) and acetonitrile (3 ml) was stirred at room temperature for 8.5 hours. The reaction mixture was concentrated to give 1-[N-(6-chloro-3-pyridylmethyl)-N-methylamino]-3-dimethylamino-1-methylamino-2-nitro-propene (Compound No. 1) (0.49 g) as a syrupy liquid.

Workup

  1. concentrationThe reaction mixture was concentrated

Sources & evidence

ORD record
ord-033e682bc3a04948a875b46231afa2e8
Source dataset
uspto-grants-1995_08
Patent number
US05438065

Reaction notes

Loading…