N-(tert-butoxycarbonyl)glycine → HCID 22855152, compound

HRID 1755798Notes

Reaction equation

HRID 1755798 reaction equation
[OH:1][C@H:2]([CH3:46])[CH2:3][NH:4][C:5]([CH3:45])([CH3:44])[CH2:6][C:7]([NH:9][C@H:10]1[C:16](=[O:17])[N:15]([CH2:18][C:19]2[CH:24]=[CH:23][C:22]([C:25]3[CH:30]=[CH:29][CH:28]=[CH:27][C:26]=3[CH2:31][NH:32][C:33]([O:35][C:36]([CH3:39])([CH3:38])[CH3:37])=[O:34])=[CH:21][CH:20]=2)[C:14]2[CH:40]=[CH:41][CH:42]=[CH:43][C:13]=2[S:12][CH2:11]1)=[O:8].[C:47]([O:51][C:52]([NH:54][CH2:55][C:56](O)=[O:57])=[O:53])([CH3:50])([CH3:49])[CH3:48]>>[C:47]([O:51][C:52]([NH:54][CH2:55][C:56]([O:1][C@H:2]([CH3:46])[CH2:3][NH:4][C:5]([CH3:45])([CH3:44])[CH2:6][C:7]([NH:9][C@H:10]1[C:16](=[O:17])[N:15]([CH2:18][C:19]2[CH:24]=[CH:23][C:22]([C:25]3[CH:30]=[CH:29][CH:28]=[CH:27][C:26]=3[CH2:31][NH:32][C:33]([O:35][C:36]([CH3:38])([CH3:39])[CH3:37])=[O:34])=[CH:21][CH:20]=2)[C:14]2[CH:40]=[CH:41][CH:42]=[CH:43][C:13]=2[S:12][CH2:11]1)=[O:8])=[O:57])=[O:53])([CH3:50])([CH3:49])[CH3:48]

Participants

3

Reactant 2

HCID 78288N-(tert-butoxycarbonyl)glycineHCID 22855150HCID 22855150, compound

Product 1

HCID 22855152HCID 22855152, compound

Procedure

This intermediate is prepared from the intermediate obtained in Step B and N-t-butoxycarbonyl glycine according to the procedure described in Example 9, Step C.

Sources & evidence

ORD record
ord-b8fd2b95e2db4a61bcd30ca4aca1601b
Source dataset
uspto-grants-1995_08
Patent number
US05438136

Reaction notes

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