HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → N-benzyloxycarbonyl-N-allyl-D-alanine t-butyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Benzyl chloroformate | HCID 10387 | — |
| Reactant | N-allyl-D-alanine t-butyl ester | HCID 54332184 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | N-benzyloxycarbonyl-N-allyl-D-alanine t-butyl ester | HCID 54427579 | — |
Reaction Steps
N-Allyl-D-alanine t-butyl ester (69) is treated with 1.1 equivalents of benzyl chloroformate and 1.1 equivalents of triethylamine in methylene chloride at room temperature overnight. After evaporation of solvent, the product is purified by silica gel chromatography to give (70).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05438118 |
| Source dataset | uspto-grants-1995_08 |
| ORD ID | ord-2959b5d665364fc0820cbc1a7f2c17b0 |
| Source note | uspto-grants-1995_08 |