HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,4-Dimethyl 2-oxobutanedioate → HCID 178498583, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,4-Dimethyl 2-oxobutanedioate | HCID 230407 | — |
| Reactant | 3-Amino-5-methyl-4H-1,2,4-triazole | HCID 234610 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | HCID 178498583 | HCID 178498583 | 30.7% |
Reaction Steps
3-Amino-5-methyl-1H-s-triazole (112 mg) and 320 mg of dimethyl 2-oxo-succinate are dissolved in 5 ml of glacial acetic acid. After boiling under reflux for 22 hours the solvent is distilled off in a vacuum. The residue is suspended in warm methanol. After cooling the product is filtered off and washed several times with methanol. After drying in a high vacuum there are obtained 73 mg of methyl 7-hydroxy-2-methyl-s-triazolo[1,5-a]pyrimidine-5-carboxylate as a beige powder, m.p.>220° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05438052 |
| Source dataset | uspto-grants-1995_08 |
| ORD ID | ord-462c67e82b854504a170aa474b32d2a9 |
| Source note | uspto-grants-1995_08 |