HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Diethyl Ether → 3-Methyl-7-(2-phenylethyl)pyrrolo[2,3-b]pyridine hydrobromide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Diethyl Ether | HCID 3283 | — |
| Edukt | Phenethyl bromide | HCID 7666 | — |
| Edukt | 3-Methyl-7-azaindole | HCID 10931471 | — |
| Lösungsmittel | Acetonitrile | HCID 6342 | — |
| Produkt | 3-Methyl-7-(2-phenylethyl)pyrrolo[2,3-b]pyridine hydrobromide | HCID 23207148 | 27,4% |
Reaktionsschritte
A solution of 0.3 g (2.3 mmol) 3-methylpyrrolo[2,3-b]pyridine and 0.5 g (2.7 mmol) (2-bromoethyl)benzene in 10 ml acetonitril was refluxed for 72 h. The solvent was evaporated and the solid that formed was treated with ether. Recrystalization from ethyl acetate gave 0.2 g (27%) of the title compound as a white solid.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US05439917 |
| Quelldatensatz | uspto-grants-1995_08 |
| ORD ID | ord-9bb3767162c642e5a05e45274cee7029 |
| Quellennotiz | uspto-grants-1995_08 |