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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 1756045Erstellt: 27. Oktober 2026

Diethyl Ether → 3-Methyl-7-(2-phenylethyl)pyrrolo[2,3-b]pyridine hydrobromide

https://huagongshe.com/reaction/1756045

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktDiethyl EtherHCID 3283—
EduktPhenethyl bromideHCID 7666—
Edukt3-Methyl-7-azaindoleHCID 10931471—
LösungsmittelAcetonitrileHCID 6342—
Produkt3-Methyl-7-(2-phenylethyl)pyrrolo[2,3-b]pyridine hydrobromideHCID 2320714827,4%

Reaktionsschritte

A solution of 0.3 g (2.3 mmol) 3-methylpyrrolo[2,3-b]pyridine and 0.5 g (2.7 mmol) (2-bromoethyl)benzene in 10 ml acetonitril was refluxed for 72 h. The solvent was evaporated and the solid that formed was treated with ether. Recrystalization from ethyl acetate gave 0.2 g (27%) of the title compound as a white solid.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS05439917
Quelldatensatzuspto-grants-1995_08
ORD IDord-9bb3767162c642e5a05e45274cee7029
Quellennotizuspto-grants-1995_08