HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloro-3-methyl-7-(p-fluorophenacyl)pyrrolo [2,3-b]pyridine hydrochloride → 2-Chloro-3-methyl-7-(2-(p-fluorophenyl)-2-hydroxyethyl)pyrrolo [2,3-b]pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloro-3-methyl-7-(p-fluorophenacyl)pyrrolo [2,3-b]pyridine hydrochloride | HCID 19916774 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 2-Chloro-3-methyl-7-(2-(p-fluorophenyl)-2-hydroxyethyl)pyrrolo [2,3-b]pyridine | HCID 21743861 | 99.6% |
Reaction Steps
A solution of 1,0 g (2,8 mmol) of 2-chloro-3-methyl-7-(p-fluorophenacyl)pyrrolo [2,3-b]pyridine hydrochloride in 50 ml methanol was treated with NaBH in the same manner as ex. 18 to give 0,85 g (99%) of the title compound as white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05439917 |
| Source dataset | uspto-grants-1995_08 |
| ORD ID | ord-76a8751ff4c1405c934144b7b22a52bd |
| Source note | uspto-grants-1995_08 |