Phenacyl bromide → HCID 19916810, compound

HRID 1756082Notes

Reaction equation

HRID 1756082 reaction equation
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[NH:16][C:11]3=[N:12][CH:13]=[CH:14][CH:15]=[C:10]3[C:9]=2[CH3:17])=[CH:4][CH:3]=1.[CH2:18](Br)[C:19]([C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1)=[O:20]>>[Br:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]2[N:16]=[C:11]3[N:12]([CH2:18][C:19]([C:21]4[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=4)=[O:20])[CH:13]=[CH:14][CH:15]=[C:10]3[C:9]=2[CH3:17])=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 6259Phenacyl bromideHCID 22477214HCID 22477214, compound

Product 1

HCID 19916810HCID 19916810, compound

Procedure

The title compound was prepared from 2-(p-bromophenyl)-3-methyl-pyrrolo-[2,3-b]pyridine and phenacylbromide on a 1.7 mmol scale according to the procedure described in example 8 yielding 620 mg (74%).

Sources & evidence

ORD record
ord-8a126bc95f51475db8a8dc99a498993f
Source dataset
uspto-grants-1995_08
Patent number
US05439917

Reaction notes

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