Phenacyl bromide → HCID 19916780, compound

HRID 1756083Notes

Reaction equation

[CH3:1][C:2]1[C:10]2[C:5](=[N:6][CH:7]=[CH:8][CH:9]=2)[NH:4][C:3]=1[C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1.[CH2:17](Br)[C:18]([C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1)=[O:19]>>[CH3:1][C:2]1[C:10]2[C:5]([N:6]([CH2:17][C:18]([C:20]3[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=3)=[O:19])[CH:7]=[CH:8][CH:9]=2)=[N:4][C:3]=1[C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1

Participants

Reactant 2

HCID 6259Phenacyl bromide

HCID 22477464HCID 22477464, compound

Product 1

HCID 19916780HCID 19916780, compound

Procedure

The title compound was prepared from 3-methyl-2-phenylpyrrolo[2,3-b]pyridine and phenacylbromide on a 4 mmol scale according to the procedure described in example 8 yielding 1.58 g (97%).

Sources & evidence

ORD record: ord-39debab4c1874a1280c220ff6ddbfd04
Source dataset: uspto-grants-1995_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05439917

Reaction notes

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