Phenacyl bromide → HCID 19916819, compound

HRID 1756084Notes

Reaction equation

[CH3:1][C:2]1[C:10]2[C:5](=[N:6][CH:7]=[CH:8][CH:9]=2)[NH:4][C:3]=1[C:11]1[CH:16]=[CH:15][C:14]([CH3:17])=[CH:13][CH:12]=1.[CH2:18](Br)[C:19]([C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1)=[O:20]>>[CH3:1][C:2]1[C:10]2[C:5]([N:6]([CH2:18][C:19]([C:21]3[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=3)=[O:20])[CH:7]=[CH:8][CH:9]=2)=[N:4][C:3]=1[C:11]1[CH:16]=[CH:15][C:14]([CH3:17])=[CH:13][CH:12]=1

Participants

Reactant 2

HCID 6259Phenacyl bromide

HCID 22477208HCID 22477208, compound

Product 1

HCID 19916819HCID 19916819, compound

Procedure

The title compound was prepared from 3-methyl-2-(p-methylphenyl)-pyrrolo[2,3-b]pyridine and phenacyl bromide on a 3 mmol scale according to the procedure described in example 8 yielding 1.21 g (96%).

Sources & evidence

ORD record: ord-3051cd595841450b98d9aeaecae5df87
Source dataset: uspto-grants-1995_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05439917

Reaction notes

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