Phenacyl bromide → HCID 19916772, compound

HRID 1756085Notes

Reaction equation

HRID 1756085 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[NH:17][C:12]3=[N:13][CH:14]=[CH:15][CH:16]=[C:11]3[C:10]=2[CH3:18])=[CH:5][CH:4]=1.[CH2:19](Br)[C:20]([C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1)=[O:21]>>[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[N:17]=[C:12]3[N:13]([CH2:19][C:20]([C:22]4[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=4)=[O:21])[CH:14]=[CH:15][CH:16]=[C:11]3[C:10]=2[CH3:18])=[CH:5][CH:4]=1

Participants

3

Reactant 2

HCID 6259Phenacyl bromideHCID 22477499HCID 22477499, compound

Product 1

HCID 19916772HCID 19916772, compound

Procedure

The title compound was prepared from 2-(p-methoxyphenyl)-3-methyl-pyrrolo[2,3-b]pyridine and phenacylbromide on a 10 mmol scale according to the procedure described in example 8 yielding 4.02 g (92% ).

Sources & evidence

ORD record
ord-ca30d301ac4647c099045b1c429f8834
Source dataset
uspto-grants-1995_08
Patent number
US05439917

Reaction notes

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