Potassium bisulfate → HCID 14852374, compound

Participants

Reaction Steps

1-benzyl-5-(1-hydroxy-1,3-diphenylpropyl)-1H-imidazole is treated with anhydrous potassium hydrogen sulphate at 150° C. as described in Example 7 e). The double bond of the obtained intermediate, 1-benzyl-5-(1,3-diphenyl-1-propenyl)-1H-imidazole, is hydrogenated as described in Example 7 f). M.p. of the hydrochloride salt is 154°-174° C. (from diethylether).

Provenance & Evidence