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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1756145Generated: October 25, 2026

Formaldehyde → HCID 54204491, compound

https://huagongshe.com/reaction/1756145

Reaction equation

Participants

RoleNameHCIDCharge
ReactantFormaldehydeHCID 712—
ReactantDimethylamine, hydrochlorideHCID 10473—
Reactant4,6-DimethylpyrimidineHCID 15257—
ReactantHCID 19349509HCID 19349509—
SolventWaterHCID 962—
ProductHCID 54204491HCID 54204491—

Reaction Steps

The compound 4,6-divinylpyrimidine is miscible with water and can be prepared according to the synthetic scheme illustrated in FIG. 1. As shown, in a two-step process, 4,6-dimethylpyrimidine is reacted with dimethylamine hydrochloride and formaldehyde to provide the corresponding 4,6-bis(dimethylaminoethyl)pyrimidine. This dimethylaminoethyl compound is methylated and deaminated in the presence of a base to provide the desired 4,6-divinylpyrimidine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05439950
Source datasetuspto-grants-1995_08
ORD IDord-aa7cd33d6fbe49b48c4538b4afadb04c
Source noteuspto-grants-1995_08