Lithium Hydroxide → HCID 15341821, compound

Participants

Reaction Steps

The compound of Example 42 (90 mg, 0.1845 mmol) and 369 μl of 1M lithium hydroxide were added to 2.0 ml of methanol, and the reaction mixture was stirred at room temperature overnight. The solvent was removed under vacuum, 10 ml of water was added, and the solution was acidified with dilute hydrochloric acid then stirred for 1 hour. The white precipitate that formed was removed by filtration and dried at 40° C. in a vacuum oven to give the product.

Provenance & Evidence