HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Aminopyridine → HCID 22921714, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Aminopyridine | HCID 1727 | — |
| Reactant | 4-Methylmorpholine | HCID 7972 | — |
| Reactant | 2-[[(8-chlorodibenz[b,f][1,4]oxazepin-10(11H)-yl)carbonyl]amino]acetic acid | HCID 10830447 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 22921714 | HCID 22921714 | 15.3% |
Reaction Steps
By the method described in Example 5, the title compound of Example 4 (0.5 g, 1.5 mmol) in 20 mL of CH2Cl2 was converted to its mixed anhydride with NMM (0.16 mL, 1.5 mmol) and IBCF (0.2 mL, 1.5 mmol). This intermediate was condensed with 4-aminopyridine (0.21 g, 2.25 mmol) to produce the title compound (94 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05441950 |
| Source dataset | uspto-grants-1995_08 |
| ORD ID | ord-e3f0718658914e86b8b7aa9a1285333a |
| Source note | uspto-grants-1995_08 |