HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Aminopyridine → HCID 15341013, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Aminopyridine | HCID 1727 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 8-chlorodibenz[b,f][1,4]oxazepin-10(11H)carbonyl chloride | HCID 14975983 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 15341013 | HCID 15341013 | 89.3% |
Reaction Steps
By the method described in Example 18, 4-aminopyridine (1.3 g, 14.0 mmol) in 40 mL of CH2Cl2 with molecular sieves #5A (5 g) and Et3N (1.4 g, 15.0 mmol) was reacted with the title compound of Example 2 (4.1 g, 14.0 mmol) to produce 4.4 g of the title product after HPLC purification on silica gel.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05441950 |
| Source dataset | uspto-grants-1995_08 |
| ORD ID | ord-0b605e81abff4f528cdcd1cdff8b2964 |
| Source note | uspto-grants-1995_08 |