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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1756585Generated: November 1, 2026

Isatin → 2-Aminonicotinic acid

https://huagongshe.com/reaction/1756585

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIsatinHCID 7054—
Reactant86724-78-9HCID 13151387—
Product2-Aminonicotinic acidHCID 72930—

Reaction Steps

Using the procedure in Example 56 and substituting 5-fluoroisatin for isatin and 2-amino-6-fluoropyridine-3-carboxylic acid (Rogers et al. U.S. Pat. No. 4,383,851, 1983) for 2-aminonicotinic acid gives the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05441955
Source datasetuspto-grants-1995_08
ORD IDord-6e0eb5c4612043e5988a99a2f0d684b5
Source noteuspto-grants-1995_08