HuagongsheHuagongshe Chemistry Print Report · For research reference only
Isatin → 2-Aminonicotinic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Isatin | HCID 7054 | — |
| Reactant | (-)-2-Aminobutyric acid | HCID 80283 | — |
| Reactant | 2-Amino-5-chloropyridine-3-carboxylic acid | HCID 19390728 | — |
| Product | 2-Aminonicotinic acid | HCID 72930 | — |
Reaction Steps
Using the procedure in Example 56 and substituting 5-fluoroisatin for isatin and 2-amino-5-chloronicotinic acid (Abu El-Haj et al., U.S. Pat. No. 3,917,624, 1975) for 2-aminonicotinic acid gives the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05441955 |
| Source dataset | uspto-grants-1995_08 |
| ORD ID | ord-3146c6ebbfba4bd79266e556fded5967 |
| Source note | uspto-grants-1995_08 |