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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1756640Generated: October 28, 2026

2-Thiopheneboronic acid → 5-Trifluoromethyl-1H-benzimidazole

https://huagongshe.com/reaction/1756640

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Thiopheneboronic acidHCID 2733960—
ReactantHCID 19390962HCID 19390962—
Product5-Trifluoromethyl-1H-benzimidazoleHCID 349444—

Reaction Steps

2-Amino-1-]3(2-thienyl)phenyl]-5-trifluoromethylbenzimidazole was prepared from 1-(2-amino-5-trifluoromethyl-1-benzimidazolyl)-3-iodobenzene and 2-thienylboronic acid according method B. mp 89°-91° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05441969
Source datasetuspto-grants-1995_08
ORD IDord-d2f8636b74dd4a27b67a0f273e949f68
Source noteuspto-grants-1995_08