Hydrochloric Acid → HCID 178479112, compound

HRID 1756641Notes

Reaction equation

[NH2:1][C:2]1[N:6]([C:7]2[C:12]([C:13]3[C:14]([O:19]C)=[N:15][CH:16]=[CH:17][CH:18]=3)=[CH:11][CH:10]=[CH:9][CH:8]=2)[C:5]2[CH:21]=[CH:22][CH:23]=[CH:24][C:4]=2[N:3]=1.[ClH:25]>>[ClH:25].[NH2:1][C:2]1[N:6]([C:7]2[C:12]([C:13]3[C:14]([OH:19])=[N:15][CH:16]=[CH:17][CH:18]=3)=[CH:11][CH:10]=[CH:9][CH:8]=2)[C:5]2[CH:21]=[CH:22][CH:23]=[CH:24][C:4]=2[N:3]=1

Participants

Reactant 2

HCID 313Hydrochloric Acid

HCID 22068809HCID 22068809, compound

Product 1

HCID 178479112HCID 178479112, compound

Procedure

2-Amino-1-[6-(2-hydroxypyridyl)phenyl]benzimidazole hydrochloride was prepared from 2-amino-1-[6-(2-methoxypyridyl)phenyl]benzimidazole by refluxing in 25% aqueous hydrochloric acid. mp 215°-217° C.

Sources & evidence

ORD record: ord-a3d8ed0abfb24a0ca224e221bf49ac67
Source dataset: uspto-grants-1995_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05441969

Reaction notes

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