4-Iodoaniline → 1-(2-Amino-1-benzimidazolyl)-4-iodobenzene

HRID 1756654Notes

Reaction equation

HRID 1756654 reaction equation
[I:1][C:2]1[CH:8]=[CH:7][C:5]([NH2:6])=[CH:4][CH:3]=1.[NH2:9][C:10]1N(C2C=CC=C(I)C=2)[C:13]2[CH:22]=[CH:23][CH:24]=[CH:25][C:12]=2[N:11]=1>>[NH2:9][C:10]1[N:6]([C:5]2[CH:7]=[CH:8][C:2]([I:1])=[CH:3][CH:4]=2)[C:13]2[CH:22]=[CH:23][CH:24]=[CH:25][C:12]=2[N:11]=1

Participants

3

Reactant 2

HCID 108934-IodoanilineHCID 193909601-(3-Iodophenyl)-1H-benzimidazol-2-amine

Product 1

HCID 193909441-(2-Amino-1-benzimidazolyl)-4-iodobenzene

Procedure

1-(2-Amino-1-benzimidazolyl)-4-iodobenzene (mp 212°-214° C. ) was prepared from 4-iodoaniline via 4-iodo-2'-nitrodiphenylamine (mp 174°-175° C.) and 4-iodo-2'-aminodiphenylamine (mp 127°-128° C.), in analogy with the sequence used in the preparation of 1-(2-amino-1-benzimidazolyl)-3-iodobenzene.

Sources & evidence

ORD record
ord-4672dfb4a28f432baa5544e935121665
Source dataset
uspto-grants-1995_08
Patent number
US05441969

Reaction notes

Loading…