HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylamine → 1-Acetyl-4-(4-dimethylaminobenzoylmethyl)piperidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylamine | HCID 674 | — |
| Reactant | 1-Acetyl-4-(4-fluorobenzoylmethyl)piperidine | HCID 10084118 | — |
| Product | 1-Acetyl-4-(4-dimethylaminobenzoylmethyl)piperidine | HCID 19390847 | — |
Reaction Steps
A mixture of 1.84 g of 1-acetyl-4-(4-fluorobenzoylmethyl)piperidine and 6 ml of a 50% aqueous solution of dimethylamine was stirred at room temperature for 3 days and the reaction mixture was worked up as in Example 1 to give 1.8 g of colorless crystals melting at 136° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05441967 |
| Source dataset | uspto-grants-1995_08 |
| ORD ID | ord-551b2a18819446158dae6708cb7ef18e |
| Source note | uspto-grants-1995_08 |