Hydrochloric Acid → HCID 76309304, compound

HRID 1756737Notes

Reaction equation

[O:1]([C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][C:9]=1[C:14](=[N:18][O:19][CH3:20])[C:15]([NH2:17])=[O:16])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.Cl>C1(C)C=CC=CC=1>[O:1]([C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][C:9]=1/[C:14](=[N:18]\[O:19][CH3:20])/[C:15]([NH2:17])=[O:16])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

Conditions

Temperature: 80 °C

Procedure

2-(2-phenoxyphenyl)-2-methoxyiminoacetamide (E/Z=14/86) (0.27 g, 1 mmol) was dissolved in toluene (1 ml). Conc. hydrochloric acid (0.17 ml) was added, and the mixture was heated at 80° C. for 2 hours. A part of the mixture was sampled, and the toluene was evaporated under reduced pressure to give (E)-2-(2-phenoxyphenyl)-2-methoxyiminoacetamide. The E/Z ratio of it was determined (E/Z=98/2).

Workup

aliquotA part of the mixture was sampled
customthe toluene was evaporated under reduced pressure

Sources & evidence

ORD record: ord-30b0017faad742568dd8245ffc27137a
Source dataset: uspto-grants-1995_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05442063

Reaction notes

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