Sodium hydride → HCID 18959463, compound

HRID 1756845Notes

Reaction equation

HRID 1756845 reaction equation
[CH2:1]([O:9][N:10]1[C:15]([CH3:17])([CH3:16])[CH2:14][CH:13]([O:18][CH2:19][CH:20]2[O:22][CH2:21]2)[CH2:12][C:11]1([CH3:24])[CH3:23])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]CC.[OH:25][CH:26]1[CH2:31][C:30]([CH3:33])([CH3:32])[N:29]([O:34][CH:35]2[CH2:40][CH2:39][CH2:38][CH2:37][CH2:36]2)[C:28]([CH3:42])([CH3:41])[CH2:27]1.[H-].[Na+]>>[CH:1]1([O:9][N:10]2[C:15]([CH3:16])([CH3:17])[CH2:14][CH:13]([O:18][CH2:19][CH:20]([OH:22])[CH2:21][O:25][CH:26]3[CH2:31][C:30]([CH3:32])([CH3:33])[N:29]([O:34][CH:35]4[CH2:40][CH2:39][CH2:38][CH2:37][CH2:36]4)[C:28]([CH3:42])([CH3:41])[CH2:27]3)[CH2:12][C:11]2([CH3:24])[CH3:23])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1

Participants

4

Reactant 3

HCID 24758Sodium hydrideHCID 113228111-Cyclohexyloxy-2,2,6,6-tetramethyl-piperidin-4-olHCID 539867304-(2,3-Epoxypropoxy)-1-octyloxy-2,2,6,6-tetramethylpiperidine

Product 1

HCID 18959463HCID 18959463, compound

Procedure

The title compound is prepared by the reaction of 1-(1-cyclohexyloxy-2,2,6,6-tetramethylpiperidin-4-yloxy)-2,3-epoxypropane (prepared in Example 11) with 4-hydroxy-1-cyclohexyloxy-2,2,6,6-tetramethylpiperidine (prepared in Example 5) and sodium hydride.

Sources & evidence

ORD record
ord-c298a43c97bb4ed4b00b9e96e2d4e39f
Source dataset
uspto-grants-1995_08
Patent number
US05442071

Reaction notes

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