反应详情

2-Pyridylacetonitrile (10.0 g; 0.084 moles) was dissolved in p-dioxane (200 mL) and then treated with tributyltin azide (30.9 g; 0.093 moles) in one portion. The solution was refluxed for 20 hours, cooled to room temperature, and then concentrated in vacuo. The viscous syrup was taken up in ethyl ether and treated with gaseous HCl for over 15 minutes, affording a maroon-colored precipitate that was recrystallized from ethanol. Yield: 9.1 g (55%).

1. temperatureThe solution was refluxed for 20 hours
2. concentrationconcentrated in vacuo
3. additiontreated with gaseous HCl for over 15 minutes
4. customaffording a maroon-colored precipitate that
5. customwas recrystallized from ethanol