Diisopropylaniline → 5-dodecyl-alpha,alpha-dimethyl-N-(2,4,6-trimethoxyphenyl)-2H-tetrazole-2-acetamide
Reaction equation
[CH2:1]([C:13]1[N:14]=[N:15][N:16]([C:18]([CH3:23])([CH3:22])[C:19]([OH:21])=O)[N:17]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12].C(C1N=NN(CC(O)=O)N=1)CCCCCCCCC.[CH3:43][O:44][C:45]1[CH:51]=[C:50]([O:52][CH3:53])[CH:49]=[C:48]([O:54][CH3:55])[C:46]=1[NH2:47].C(C1C=CC=C(C(C)C)C=1N)(C)C>>[CH2:1]([C:13]1[N:14]=[N:15][N:16]([C:18]([CH3:23])([CH3:22])[C:19]([NH:47][C:46]2[C:48]([O:54][CH3:55])=[CH:49][C:50]([O:52][CH3:53])=[CH:51][C:45]=2[O:44][CH3:43])=[O:21])[N:17]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12]Participants
5
Procedure
When in the general procedure of Example 88 an appropriate amount of 5-dodecyl-α,α-dimethyl-2H-tetrazole-2-acetic acid was substituted for 5-decyl-2H-tetrazole-2-acetic acid and 2,4,6-trimethoxyaniline was substituted for 2,6-diisopropylaniline, the title compound was obtained.
Sources & evidence
- ORD record
- ord-b70cd884d68e45f88327be63319a8bdf
- Source dataset
- uspto-grants-1995_08
- Patent number
- US05441975
Reaction notes
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