Diisopropylaniline → N-(2,6-Diisopropyl-phenyl)-2-(3-dodecyl-isoxazol-5-yl)-2-phenyl-acetamide

HRID 1756975Notes

Reaction equation

HRID 1756975 reaction equation
[CH2:1]([C:13]1[CH:17]=[C:16]([CH:18]([C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=2)[C:19]([OH:21])=O)[O:15][N:14]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12].C(C1ON=C(C(C2C=CC=CC=2)C(O)=O)C=1)CCCCCCCCCCC.[CH3:55][CH:56]([C:58]1[CH:64]=[CH:63][CH:62]=[C:61]([CH:65]([CH3:67])[CH3:66])[C:59]=1[NH2:60])[CH3:57]>>[CH2:1]([C:13]1[CH:17]=[C:16]([CH:18]([C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=2)[C:19]([NH:60][C:59]2[C:61]([CH:65]([CH3:66])[CH3:67])=[CH:62][CH:63]=[CH:64][C:58]=2[CH:56]([CH3:57])[CH3:55])=[O:21])[O:15][N:14]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12]

Participants

4

Reactant 3

HCID 32484DiisopropylanilineHCID 105232775-Dodecyl-alpha-phenyl-3-isoxazole acetic acidHCID 108330563-Dodecyl-alpha-phenyl-5-isoxazole acetic acid

Product 1

HCID 10554232N-(2,6-Diisopropyl-phenyl)-2-(3-dodecyl-isoxazol-5-yl)-2-phenyl-acetamide

Procedure

In a manner similar to Example 128, a mixture of 3-dodecyl-α-phenyl-5-isoxazole acetic acid and 5-dodecyl-α-phenyl-3-isoxazole acetic acid was condensed with 2,6-bis(1-methylethyl)aniline to give after chromatography pure title compound; mp 115°-117° C.

Sources & evidence

ORD record
ord-0b0b6592ca7f45fd8edb69e63e25b8db
Source dataset
uspto-grants-1995_08
Patent number
US05441975

Reaction notes

Loading…