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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1757083Generated: October 28, 2026

Butyl iodide → N-(tert-Butyl)-5-isobutylthiophene-2-sulfonamide

https://huagongshe.com/reaction/1757083

Reaction equation

Participants

RoleNameHCIDCharge
ReactantButyl iodideHCID 10962—
Reactant5-Butyl-N-tert-butylthiophene-2-sulfonamideHCID 11993904—
SolventEthyl AcetateHCID 8857—
ProductN-(tert-Butyl)-5-isobutylthiophene-2-sulfonamideHCID 11482758—

Reaction Steps

The titled compound was prepared using the procedure described for the synthesis of 5-butyl-2-(N-t-butylaminosulfonyl)-thiophene by substituting isobutyliodide for butyliodide. Rf=0.37 (6:1 Hex/EtOAc).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05444067
Source datasetuspto-grants-1995_08
ORD IDord-93aa92d9526d484cb2a5aece2235cd0c
Source noteuspto-grants-1995_08