HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl iodide → HCID 19390114, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl iodide | HCID 6328 | — |
| Reactant | 2-[(Dimethylamino)methyl]-4,6-difluorophenol | HCID 19390101 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | HCID 19390114 | HCID 19390114 | 87% |
Reaction Steps
74 g (0.40 mol) of 3,5-difluoro-2-hydroxy-N,N-dimethylbenzylamine was dissolved in 300 ml of chloroform, and 200 ml of methyl iodide was added thereto. The mixture was heated under reflux for 3 hr to deposit a yellow precipitate. The precipitate was recovered by filtration to prepare 114 g (yield: 87%) of the intended product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05444083 |
| Source dataset | uspto-grants-1995_08 |
| ORD ID | ord-930c03ff64fb4ccd92b94561a23781ae |
| Source note | uspto-grants-1995_08 |