HCID 15234843, compound → HCID 77768196, compound

HRID 1757224Notes

Reaction equation

HRID 1757224 reaction equation
[OH:1][CH:2]1[CH2:14][CH2:13][C:5]2([CH2:10][CH2:9][CH:8]([CH:11]=O)[CH2:7][CH2:6]2)[CH2:4][CH2:3]1.[O:15]=[C:16]1[CH:20]=[C:19]([CH2:21]P(=O)(OC)OC)[CH2:18][O:17]1>>[OH:1][CH:2]1[CH2:14][CH2:13][C:5]2([CH2:10][CH2:9][CH:8]([CH:11]=[CH:21][C:19]3[CH2:18][O:17][C:16](=[O:15])[CH:20]=3)[CH2:7][CH2:6]2)[CH2:4][CH2:3]1

Participants

3

Reactant 2

HCID 15234843HCID 15234843, compoundHCID 193900319-Hydroxyspiro[5.5]undecane-3-carboxaldehyde

Product 1

HCID 77768196HCID 77768196, compound

Procedure

Using the same reaction conditions described in Ex. 2 and 9-hydroxy-3-formyl-spiro[5.5]undecane (I-bc, Ex. 50) and dimethyl (2-oxo-[5H]-4-furyl)methylphosphonate (intermediate described in Ex. 2) as starting materials, the title compound (EZ)-9-hydroxy-3-(2-(2-oxo-[5H]-4-furyl)vinyl)-spiro-[5.5]undecane (I-ai) was obtained as an amorphous solid, identical to the one above described.

Workup

  1. customthe same reaction conditions

Sources & evidence

ORD record
ord-b7a3ec1f24014606a4b156366e7335a7
Source dataset
uspto-grants-1995_08
Patent number
US05444082

Reaction notes

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