2-Hepten-4-yne, 1-bromo-6,6-dimethyl- → (E)-2-(6,6-dimethyl-2-hepten-4-ynyl)-3-[3-[3-(3-thienyl)phenylmethoxy]phenyl]propionic acid methyl ester

Participants

Reaction Steps

(E,E)-2-(6,6-dimethyl-2-hepten-4-ynyl)-3-[3-[2-[3-(3-thienyl)phenyl]ethenyl]phenyl]propionic acid methyl ester, (E)-2-(6,6-dimethyl-2-hepten-4-ynyl)-3-[3-[4-(3-thienyl)-2-thienylmethoxy]phenyl]propionic acid methyl ester, (E)-2-(6,6-dimethyl-2,4-heptadiynyl)-3-[3-[2-[3-(3-thienyl)phenyl]ethenyl]phenyl]propionic acid methyl ester, (E)-2-(6,6-dimethyl-2-hepten-4-ynyl)-7-[3-(3-thienyl)phenoxy]heptanoic acid methyl ester and (E,E)-2-(6,6-dimethyl-2-hexen-4-ynyl)-8-[3-(3-thienyl)phenyl]-7-octenoic acid methyl ester are obtained by carrying out the same reactions as in Referential Example 4 except that 6,6-dimethyl-2,4-heptadiynyl bromide and/or (E)-3-[3-[2-[3-(3-bromomethylphenyl)ethenyl]phenyl]thiophene, 2-(3-bromomethylphenoxymethyl)-4-(3-thienyl)thiophene, 3-[3-(5-iodopentanoxy)phenyl]thiophene or (E)-3-[3-(6-iodo-1-hexenyl)phenyl]thiophene are used, respectively, in place of (E)-6,6-dimethyl-2-hepten-4-ynyl bromide and/or 3-[3-(3-bromomethylphenoxymethyl)phenyl]thiophene which are the raw material compounds used in the above reaction.

Provenance & Evidence