HRID1757366

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID957

1-Octanol

C8H18O

结构：CC(C)(C)[Si](Oc1ccc(-c2ncc(O)cc2F)cc1)(c1ccccc1)c1ccccc1

HCID19387531

未命名化合物

结构：CC(C)(C)[Si](Oc1ccc(-c2ncc(Br)cc2F)cc1)(c1ccccc1)c1ccccc1

HCID19387540

未命名化合物

PRODUCTS

生成物

结构：CCCCCCCCOc1cnc(-c2ccccc2O[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)c(F)c1

HCID19387552

未命名化合物

PROCEDURE

实验过程

5-bromo-2-(4-tert-butyldiphenylsilyloxyphenyl)-3-fluoropyridine is converted analogously to Example 2 into 2-(4-tert-butyldiphenylsilyloxyphenyl)-3-5-hydroxypyridine. ##STR32## 2-(4-tert-butyldiphenylsilyloxyphenyl)-3-fluoro-5-hydroxypyridine and octanol are reacted analogously to Example 2 to give 2-(tert-butyldiphenylsilyloxyphenyl)-3-fluoro-5-octyloxypyridine.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-b5bbc95f787d4e9da71b9ed0b80b2e88
来源数据集: uspto-grants-1995_08
DOI: 10.6084/m9.figshare.5104873.v1
专利: US05445763
来源说明: uspto-grants-1995_08

反应 SMILES

BrC1C=C(F)C([C:8]2[CH:13]=[CH:12][C:11]([O:14][Si:15]([C:28]([CH3:31])([CH3:30])[CH3:29])([C:22]3[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=3)[C:16]3[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=3)=[CH:10][CH:9]=2)=NC=1.[Si](OC1C=CC([C:57]2[C:62]([F:63])=[CH:61][C:60]([OH:64])=[CH:59][N:58]=2)=CC=1)(C(C)(C)C)(C1C=CC=CC=1)C1C=CC=CC=1.[CH2:65](O)[CH2:66][CH2:67][CH2:68][CH2:69][CH2:70][CH2:71][CH3:72]>>[Si:15]([O:14][C:11]1[CH:10]=[CH:9][CH:8]=[CH:13][C:12]=1[C:57]1[C:62]([F:63])=[CH:61][C:60]([O:64][CH2:65][CH2:66][CH2:67][CH2:68][CH2:69][CH2:70][CH2:71][CH3:72])=[CH:59][N:58]=1)([C:28]([CH3:30])([CH3:31])[CH3:29])([C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1)[C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1