Benzyl Bromide → HCID 19387979, compound

HRID 1757469Notes

Reaction equation

HRID 1757469 reaction equation
[C:1]12([C:11]3[CH:12]=[C:13]([CH:18]=[CH:19][C:20]=3[OH:21])[C:14]([O:16][CH3:17])=[O:15])[CH2:10][CH:5]3[CH2:6][CH:7]([CH2:9][CH:3]([CH2:4]3)[CH2:2]1)[CH2:8]2.[CH2:22](Br)[C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1>>[C:1]12([C:11]3[CH:12]=[C:13]([CH:18]=[CH:19][C:20]=3[O:21][CH2:22][C:23]3[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=3)[C:14]([O:16][CH3:17])=[O:15])[CH2:2][CH:3]3[CH2:9][CH:7]([CH2:6][CH:5]([CH2:4]3)[CH2:10]1)[CH2:8]2

Participants

3

Reactant 2

HCID 7498Benzyl BromideHCID 14852531HCID 14852531, compound

Product 1

HCID 19387979HCID 19387979, compound

Procedure

57 g (200 mM) of methyl 3-(1-adamantyl)-4-hydroxybenzoate are treated with benzyl bromide under the conditions described in Example 5(a) to lead to 69.5 g (92.4%) of the expected derivative, of melting point 127° C.

Sources & evidence

ORD record
ord-cf73c58d882540e3bc5b771a0fa37acd
Source dataset
uspto-grants-1995_08
Patent number
US05446059

Reaction notes

Loading…