HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 9980291, compound → 1-butyl-2-{2'-[2-(1-methyl-1-phenylethyl)-2H-tetrazol-5-yl]biphenyl-4-ylmethyl}1H-indole-3-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 9980291 | HCID 9980291 | — |
| Reactant | 1-butylindole-3-carboxylic Acid | HCID 10376290 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Product | 1-butyl-2-{2'-[2-(1-methyl-1-phenylethyl)-2H-tetrazol-5-yl]biphenyl-4-ylmethyl}1H-indole-3-carboxylic acid | HCID 10370781 | — |
Reaction Steps
reacting the 4-bromomethyl-2'-[2-(1methyl-1-phenylethyl)-2H-tetrazol-5-yl]biphenyl with 2-transmetalated 1-but-1-yl-1H-indole-3-carboxylic acid in the presence of phosphinated palladium catalyst to give 1-butyl-2-[2'-(2-(1-methyl-1-phenylethyl)-2H-tetrazol-5-yl)biphenyl-4-ylmethyl]-1H-indole-3-carboxylic acid; and
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05446121 |
| Source dataset | uspto-grants-1995_08 |
| ORD ID | ord-544fe69aadc748b98e4519e45f62f4f4 |
| Source note | uspto-grants-1995_08 |