HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 2-(Chloromethyl)anisole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 2-Methoxybenzyl alcohol | HCID 69154 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 2-(Chloromethyl)anisole | HCID 81495 | — |
Reaction Steps
In a nitrogen atmosphere, 2.00 g (14.5 mmol.) of 2-methoxybenzyl alcohol was dissolved in 10 ml of dichloromethane. The obtained solution was placed in an ice-bath, and to this was dropwise added a solution of 1.06 ml (14.6 mmol.) of thionyl chloride in 2 ml of dichloromethane.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05446146 |
| Source dataset | uspto-grants-1995_08 |
| ORD ID | ord-3de5538774274086983faba912e5ce46 |
| Source note | uspto-grants-1995_08 |