HCID 10755522, compound → HCID 10803922, compound

HRID 1757569Notes

Reaction equation

HRID 1757569 reaction equation
[Cl:1][C:2]1[CH:18]=[C:6]([C:7]([NH:9][CH2:10][CH2:11][CH2:12][N:13]([CH2:16][CH3:17])[CH2:14][CH3:15])=[O:8])[C:5]([OH:19])=[CH:4][CH:3]=1.O1CC[CH2:23]OO1>FC(F)(F)C(O)=O>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[O:19][CH2:23][N:9]([CH2:10][CH2:11][CH2:12][N:13]([CH2:16][CH3:17])[CH2:14][CH3:15])[C:7](=[O:8])[C:6]=2[CH:18]=1

Participants

4

Reactant 2

HCID 10755522HCID 10755522, compoundHCID 19593658CID 19593658

Product 1

HCID 10803922HCID 10803922, compound

Reagents, catalysts & solvents 1

HCID 6422Trifluoroacetic acidSolvent

Procedure

1.70 Grammes (6.0 mmoles) of 5-chloro-N-[3-(diethylamino)propyl]salicylamide and 540 milligrammes (6.0 mmoles) of trioxane are dissolved in 30 ml of trifluoroacetic acid and thereaction mixture is kept at room temperature for 16 hours.

Sources & evidence

ORD record
ord-73c2c0bfdb0e42d1b46f0a420c2af01f
Source dataset
uspto-grants-1995_08
Patent number
US05446152

Reaction notes

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