Ethyl cyanoacetate → HCID 54021516, compound

HRID 1757655Notes

Reaction equation

HRID 1757655 reaction equation
[OH:1][C:2]1[CH:3]=[C:4]([CH:7]=[C:8]([N+:11]([O-:13])=[O:12])[C:9]=1[OH:10])[CH:5]=O.[C:14]([CH2:16][C:17]([O:19][CH2:20][CH3:21])=[O:18])#[N:15].C([O-])(=O)C.[NH4+]>C(O)C>[C:14]([C:16](=[CH:5][C:4]1[CH:7]=[C:8]([N+:11]([O-:13])=[O:12])[C:9]([OH:10])=[C:2]([OH:1])[CH:3]=1)[C:17]([O:19][CH2:20][CH3:21])=[O:18])#[N:15]

Participants

5

Reactant 3

HCID 7764Ethyl cyanoacetateHCID 517165Ammonium AcetateHCID 57489573,4-Dihydroxy-5-nitrobenzaldehyde

Product 1

HCID 54021516HCID 54021516, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

The procedure described in Example 4 was repeated using 1.0 g of 3,4-dihydroxy-5-nitrobenzaldehyde, 0.9 g of ethyl cyanoacetate and 0.15 g of ammonium acetate in 10 ml of ethanol. Yield 0.87 g (57%), m.p. 205°-210° C.

Sources & evidence

ORD record
ord-b235885bcc3b4a9c866a2538d6d84cc2
Source dataset
uspto-grants-1995_08
Patent number
US05446194

Reaction notes

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