反应详情

To a solution of 4.6 g of 3-nitro-5-(octadecyloxy)phenylcarbamic acid dimethylethyl ester in 100 ml of methylene chloride stirred at room temperature was added 20 ml of trifluoroacetic acid. The reaction mixture was kept at room temperature for 3.5 hours and the solvent was then removed at reduced pressure. The residue was treated with water and the product was filtered and recrystallized from ethyl acetate-hexane to give 3.6 g (97% yield, mp 106°-108°) of 3-nitro-5-(octadecyloxy)benzenamine.

1. customthe solvent was then removed at reduced pressure
2. additionThe residue was treated with water
3. filtrationthe product was filtered
4. customrecrystallized from ethyl acetate-hexane