HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → ((4-Phenylbutyl)hydroxyphosphoryl)acetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | [Ethoxy(4-phenylbutyl)phosphoryl]acetic acid | HCID 13136848 | — |
| Solvent | Tetrahydrofuran hexane | HCID 21883165 | — |
| Product | ((4-Phenylbutyl)hydroxyphosphoryl)acetic acid | HCID 13102401 | — |
Reaction Steps
[Ethoxy(4-phenylbutyl)phosphinyl]acetic acid from Example 1(b), is further saponified by heating with excess sodium hydroxide, acidification and recrystallization of the product from tetrahydrofuran/hexane to obtain [hydroxy(4-phenylbutyl)phosphinyl]acetic acid; m.p. 109.5°-110°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04371526 |
| Source dataset | uspto-grants-1983_02 |
| ORD ID | ord-24d21d33831943fcbfd5a502787f903a |
| Source note | uspto-grants-1983_02 |