Adipic Acid → HCID 70523839, compound

Participants

Reaction Steps

A mixture of 10 g of 8-(2,3-epoxypropyl)-7,7,9,9-tetramethyl-1,4-dioxa-8-azaspiro[4.5]decane and 2.4 g of adipic acid in 60 ml of xylene was refluxed for 16 hours. After completion of the reaction, the residue obtained by evaporating the solvent under reduced pressure from the reaction mixture was purified by column chromatography through silica gel eluted with a 1:1 by volume mixture of ethyl acetate and benzene. The desired Compound No. 208 was obtained in the form of a pale yellow, viscous product. The compound had an Rf value of 0.53 on thin-layer chromatography on silica gel developed with ethyl acetate.

Provenance & Evidence