HCID 20509903, compound → HCID 20509896, compound

HRID 1758236Notes

Reaction equation

HRID 1758236 reaction equation
[CH3:1][O:2][CH:3]([O:20][CH3:21])[CH2:4][NH:5][CH2:6][C:7]1[CH:12]=[C:11]([O:13][CH3:14])[C:10]([O:15][CH3:16])=[CH:9][C:8]=1[N+:17]([O-])=O>C(O)C.[Pd]>[CH3:21][O:20][CH:3]([O:2][CH3:1])[CH2:4][NH:5][CH2:6][C:7]1[CH:12]=[C:11]([O:13][CH3:14])[C:10]([O:15][CH3:16])=[CH:9][C:8]=1[NH2:17]

Participants

4

Reactant 1

HCID 20509903HCID 20509903, compound

Product 1

HCID 20509896HCID 20509896, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

1.2 g of N-(2,2-dimethoxyethyl)-2-nitro-4,5-dimethoxybenzylamine are dissolved in 20 ml of ethanol, and then hydrogenated at room temperature and at normal pressure, in the presence of 300 mg of palladium catalyst (10% on carbon). After filtering off the catalyst and evaporating the filtrate, the heading compound remains as an almost colourless oil, which is used in the next stage (e) without further purification.

Workup

  1. filtrationAfter filtering off the catalyst
  2. customevaporating the filtrate
  3. customis used in the next stage (e) without further purification

Sources & evidence

ORD record
ord-6a59416e0e864c34a41871beeb5bcb18
Source dataset
uspto-grants-1983_02
Patent number
US04372956

Reaction notes

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