Hydrogen Peroxide → HCID 13061934, compound

HRID 1758285Notes

Reaction equation

HRID 1758285 reaction equation
[CH3:1][N:2]1[C:6]([S:7][CH2:8][CH2:9][CH2:10][CH2:11][Br:12])=[N:5][N:4]=[N:3]1.[OH:13]O>C(O)=O.O>[Br:12][CH2:11][CH2:10][CH2:9][CH2:8][S:7]([C:6]1[N:2]([CH3:1])[N:3]=[N:4][N:5]=1)=[O:13]

Participants

5

Reactant 2

HCID 784Hydrogen PeroxideHCID 13061933HCID 13061933, compound

Product 1

HCID 13061934HCID 13061934, compound

Reagents, catalysts & solvents 2

HCID 284Formic AcidSolventHCID 962WaterSolvent

Procedure

1-Methyl-5-(4-bromobutyl)thio-1,2,3,4-tetrazole prepared in Reference Example 2 is dissolved in formic acid (50 ml). 30% Aqueous hydrogen peroxide (2.3 g) is added to the solution with stirring at room temperature and the mixture is allowed to stand at room temperature for 2 overnights. The mixture is diluted with water and extracted with chloroform. The chloroform solution is washed with water, saturated aqueous sodium bicarbonate and then saturated aqueous sodium chloride and dried over magnesium sulfate. Chloroform is distilled off to obtain 1-methyl-1,2,3,4-tetrazol-5-yl 4-bromobutyl sulfoxide (5.5 g) as colorless liquid.

Workup

  1. customto stand at room temperature for 2 overnights
  2. extractionextracted with chloroform
  3. washThe chloroform solution is washed with water, saturated aqueous sodium bicarbonate
  4. dry with materialsaturated aqueous sodium chloride and dried over magnesium sulfate
  5. distillationChloroform is distilled off

Sources & evidence

ORD record
ord-e99075e0998548848b56bc436e5dfe2e
Source dataset
uspto-grants-1983_02
Patent number
US04372953

Reaction notes

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